l-Alpha-glycerophosphatidylcholine (GPC-choline, alpha-GPC) is a water-soluble phospholipid metabolite naturally occurring in the body. Alpha-GPC passes through the blood brain barrier providing a source of choline for acetylcholine and phosphatidylcholine biosynthesis. An open multi-center clinical trial involving 2044 subjects indicated that alpha-GPC supports cognitive health and has excellent tolerability. Multiple studies suggest that alpha-GPC plays a role in enhancing mental function, neurological function, and memory. In a multi-center, randomized controlled study, 126 subjects supplemented with alpha-GPC demonstrated improved neuropsychological parameters in behavioral scales and tests.
Uses For Alpha-GPC •
- Memory And Cognitive Health: Alpha-GPC passes through the blood brain barrier providing a source of choline for acetylcholine and phosphatidylcholine biosynthesis. By supporting cell membrane fluidity and integrity, phosphatidylcholine enhances healthy neurotransmitter function and signal transduction. Alpha-GPC may support healthy phospholipid turnover in the brain, helping to counteract age-related cellular breakdown of membrane phospholipids. Acetylcholine is a key neurotransmitter in the brain supporting memory and learning. Optimal phospholipid and acetylcholine levels support cognitive, mental and cerebrovascular health.* •
- Growth Hormone Support: Alpha-GPC has the ability to potentiate growth hormone releasing hormone (GHRH), thereby supporting healthy growth hormone (GH) levels. The mechanism of support appears to involve increased cholinergic tone.*